Mesothelioma and the Dangers that it poses

Mesothelioma is one of those diseases that are still posing a challenge to the medical community. It is a type of cancer that afflicts the mesothelium, which forms a protective lining around the majority of the internal organs of the human body. Mesothelium has different nomenclature depending upon which particular organ it is covering. For instance, pleura membrane covers the lungs and the chest cavity, peritoneum covers the abdominal cavity, pericardium surrounds the heart, and tunica vaginalis testis surrounds the male internal reproductive organs, whereas tunica serosa uteri cover the female reproductive organs.

Mesothelioma is generally caused by the exposure to a particular mineral known as asbestos. The presence of asbestos particles in the mesothelium is generally responsible for the development of this cancer. Majority of the cases of mesothelioma are of those of the pleural region and the peritoneal region. The mesothelioma cases of the other regions are very few in number.

The matter of concern regarding the mesothelioma is that the asbestos fibers once lodged inside mesothelium stay dormant for a very long duration; sometimes up to 50 years. After this period of latency they start interfering with the working of the mesothelial cells. Exactly how they interfere is still under investigation, yet what is known is that the asbestos particles cause the unregulated growth of the mesothelial cells that leads to the formation of the cancerous tissues. By the time the disease is diagnosed as mesothelioma it is well into its later stages where any kind of treatment would just help in alleviating the pain and not cure the disease.

Reference: Kevin smith

The waiting game...... Cycle 2 Day 4

It only takes a small hitch to throw the oncology ward’s carefully laid schedule into chaos, and that happened yesterday. Unplanned emergency admissions delayed the start of overnight chemo for some scheduled patients. The knock-on effect today was that some of the “overnighters” were still occupying beds this morning when the day care patients’ treatment was due to start.

The waiting room was almost full when we arrived at hospital shortly before 11 am - some people had been hanging around for two hours. Our main concern was that the Velcade would go past its sell by date if there was a long delay. However, Alana found a small side room where she could do Steve’s obs and take blood samples for testing. Then, rather than stay on the ward adding to the chaos, we took ourselves off to the cafe for coffee and cakes, and read the newspaper for an hour until the test results were cleared.

It was still standing room only when we returned to Oncology at midday, and the bed allocated to Steve was occupied by someone else. But as the Velcade top-up only takes minutes to administer, he was fitted in as soon as another bed became available and was out again shortly thereafter. It seemed like we had been hanging about for ages, but only two hours had passed according to the car park ticket. Funny how time can play tricks on you.

So, cycle 2 moves forward, and in two weeks time, we’ll know whether the drug trial treatment has worked - hopefully, there’ll be something to celebrate. But we don’t have to wait until then; we have good reasons to celebrate this weekend.

Our nephew Nick and his partner Kate are expecting a baby in early 2010 - great news! We’ll raise a glass to you all this evening - much love and many congratulations! The weather looks set fair for Sunday, when we’re out to lunch with Ruth, joined by Anne and Colin visiting from Chichester - we’re looking forward to seeing you all! Europ Assistance has refunded the costs of canceling our trip to Turkey, and my regrading back in April has shown up in this month’s salary. More cards arrived in the post today to extend my birthday. The score in the third test match put the icing on the cake!

Working Towards a Mesothelioma Cure

Pericardial mesothelioma is a serious heart condition which consists of cancerous cells building up on the lining of the heart. Similarly to pleural and peritoneal mesothelioma, this is a terminal illness due to the importance of the area on which it grows.

The primary cause of pericardial mesothelioma is exposure to asbestos dust and fibres. Therefore those at risk are those who are most likely to have inhaled these deadly fibres such as construction workers and asbestos manufacturers. Those in contact with these people also have a chance of getting pericardial mesothelioma because these people may have asbestos fibres stuck to their clothes or hair.

An understanding of mesothelioma symptoms can help in the process of mesothelioma cure. Some common symptoms of mesothelioma are difficulty in breathing, chest pain, and chronic cough. However, many times this disease lies in asymptomatic in the body, which makes mesothelioma cure an impossible task.

Once detected, the chances of survival of an average mesothelioma patient are very bleak. The options for Mesothelioma cure depend upon the different stages of the disease. In the first stage the treatments options depends on factors such as patient’s age, general health, organ affected and the size of tumor.

Surgery comes in two forms; aggressive surgery and palliative procedures. Aggressive surgery is a very difficult procedure and consists of removing large chunks of cancerous cells in an attempt to gain long term control over the cancer. Palliative procedures just attempts to lessen the symptoms for the patient.

What Is The Prognosis For a mesothelioma cure?

Mesothelioma cure in these stages involves draining of the fluid to reduce discomfort. This process of treatment is known as Thorancentesis or Paracentesis. After this, the doctors use Surgery followed by radiation and chemotherapy. Treatment and efforts for mesothelioma cure can suffer a severe jolt if the disease strikes back. In that case, the treatment depends on the location of recurrence, and the patient’s medical history.

This is highly dependent on how early and how aggressively the cancer is treated. If pericardial mesothelioma is treated when it has fully developed and matured then the chances of a patient’s survival is very small. The prognosis could be only a couple of months. Research into cures of pericardial mesothelioma and all other forms of mesothelioma is being done in numerous research labs all over the USA. Many pharmaceutical companies are also working hard to research new drugs for chemotherapy. So far, research has been mostly unsuccessful.

Reference: Asbestos Related Disease, Mesothelioma Cure

Deadly Mesothelioma Cancers

What Is Asbestos?

Asbestos disease, mesothelioma cancers, lung cancers and asbestosis are the diseases caused because of asbestos exposure. Asbestos constitutes different naturally occurring fibrous minerals in some rocks and soil. It has found widespread use in industries and building materials such as fireproofing, roofing shingles, electric insulation, furnace, hot pipe covering, and friction products.

Mesothelioma cancers are the cancers affecting these membranes. The names of the cancers depend on the tissue or linings they affect. Peritoneal mesothelioma, pleural mesothelioma and pericardial mesothelioma are the names of cancers of linings of abdomen, lungs and heart, respectively. Pleural mesothelioma is the most common of all mesothelioma cancers and is found in 70 % of the mesothelioma patients. Peritoneal mesothelioma constitutes 10% to 20% of the mesothelioma patients while third type pericardial mesothelioma, is rare.

Serious Effects Of Asbestos Disease

Mesothelioma is the most serious of several asbestos-related diseases detected so far. This is because of the carcinogenic effect of asbestos particles. Asbestos can cause cancer of the lungs, esophagus, colon, rectum, stomach, vocal chords, and kidneys. About 70 percent to 80 percent of all cases of asbestos disease mesothelioma - a rare type of cancer of the mesothelium, the membrane that covers and protects most of the body internal organs -are the result of asbestos exposure at work. Asbestos disease mesothelioma may not immediately manifest.

The asbestos particles can lie dormant in the body for several years and manifest later, when the prognosis is very grim. It is possible that by the time the disease is diagnosed, the cancer may have already spread significantly. In view of health concerns all new uses of asbestos in the manufacturing industries have been banned in the United States from July 1989 onward. In particular, the use of asbestos in hand-held hair dryers was voluntarily stopped in 1979. Schools are required to test for use of asbestos roofing and it is removed or covered up.

One alarming fact about the mesothelioma cancers is its extended latency period. These cancers may remain asymptomatic in the body for even up to 50 years. Chances of survival for mesothelioma patients are rare and the average survival period after diagnosis is not more than 12-24 months. Surgery if diagnosed early, chemotherapy and radiation therapy are some common treatments for all types of mesothelioma cancers. People suffering from mesothelioma cancers can file lawsuits to recover damages for medical expenses and other damages. They can file the lawsuits against the persons and companies responsible for causing asbestos exposure.-

Reference: Asbestos Related Disease, Mesothelioma Cancers.

Mesothelioma: Beware the Dangers of Asbestos

Mesothelioma is a rare form of cancer that develops in the thin tissue layer coating many of your organs. The American Cancer Society estimates that approximately 2,000-3,000 people are diagnosed with the disease each year.

There are three types of mesothelioma cancer. Each is classified based on where it occurs in your body:

• Pleural malignant mesothelioma occurs in the tissue around your lungs. It is the most common form of the disease.
• Peritoneal mesothelioma affects the tissue around your abdomen.
• Pericardial mesothelioma occurs in the tissue around your heart.

Symptoms of Mesothelioma

The symptoms of mesothelioma vary based on the region of your body affected by the cancer. The symptoms of pleural mesothelioma include:

• Shortness of breath
• Painful breathing
• Painful coughing
• Chest pain near the rib cage
• Lumps of tissue under your chest skin
• Weight loss
• Dry cough

The symptoms of peritoneal mesothelioma are:

• Abdominal pain
• Abdominal swelling
• Change in bowel habits (frequent diarrhea or constipation)
• Lumps of tissue in abdomen
• Weight loss
• Nausea
• Vomiting

Causes of Mesothelioma

The primary cause of mesothelioma is exposure to asbestos, a harmful fiber used as insulation. People who have a high exposure to asbestos are at greatest risk of developing mesothelioma. This exposure most commonly occurs in the workplace. Frequently, blue collar jobs in mines, ship yards, manufacturing facilities, construction sites, and railway facilities place people at greatest risk of asbestos exposure.

If asbestos dust is breathed or swallowed, the fibers can settle in your lungs or stomach, resulting in an irritation that ultimately causes mesothelioma. People with very high levels of exposure to asbestos are at greater risk of contracting mesothelioma than people with lower levels of exposure. It can take as long as 30 to 40 years for the disease to develop.

Mesothelioma Lawsuits

Over the years, many lawsuits have been filed and won on behalf of people exposed to asbestos at work. If you have been diagnosed with this rare cancer, you should consult an experienced mesothelioma attorney at once to see if you have a valid claim.

It is important to choose an attorney who specializes in mesothelioma claims. This is a highly complex area of the law, and you should not trust your case to someone lacking the proper experience. Several factors complicate many of these claims, including:

• The long delay between exposure to asbestos and the development of mesothelioma
• The widespread use of asbestos in many common products
• The ability to develop mesothelioma from second-hand exposure to asbestos

These factors can often make it difficult to prove precisely where you were exposed to this dangerous fiber. You will need a lawyer who can skillfully work with these factors and still help you receive the compensation you deserve.

If you are diagnosed with mesothelioma, you are most likely looking at a lifetime of pain, medical expenses, and lost earning capacity. You should be compensated for your injuries. Why trust your mesothelioma claim to someone who is not an expert?

Reference: contact the law offices of Peter G. Angelos, P.C

Birthday Wish List

Dreams can come true
Look at me babe I’m with you
You know you gotta have hope
You know you gotta be strong

Gabrielle

In the past, Jack has berated me for not producing a birthday “list”. This year, I’ve decided to indulge myself, although it’s a wish list rather than a shopping list - the things I wish for the most aren’t those you can buy in store or on-line.

It’s also a very personal list. Hopes for world peace, freedom of speech and civil rights for all, action for climate change, an end to poverty and starvation, and other such global matters should be taken as read.

So, in no particular order, my top 10 birthday wish list is that:

1. After two cycles of treatment, Leo the tumor has (at the very least) stopped growing and (preferably) noticeably started to shrink.
2. After six cycles of treatment, Steve is feeling fit and well and is in remission.
3. The Wride family get-together at Christmas will be the best yet!
4. We can both enjoy Katie’s 21st birthday celebrations next May.
5. This time next year, Steve will come with me to collect my bus pass and we can jog home together.
6. I can send Steve a birthday card to mark is One Millionth birthday in 2011 (in binary numbers - work it out!)
7. Our ruby wedding on 1 May 2012 will be an event to remember.
8. I could turn the clock back to whenever the asbestos fibres entered Steve’s lungs and stop it happening.
9. The risks of disturbing asbestos had been recognized at the same time as its safety benefits and commercial potential.
10. Velcade works, not just for Steve, but for everyone with mesothelioma and that the cost of the drug plummets as its use increases.

Big wheel keeps on turning ...Cycle 2, Day 1

The big wheel keeps on turning
On a simple line day by day
The earth spins on its axis
One man struggle while another relaxes

Massive Attack

The big wheel keeps on turning….here we go again with chemo (although it’s not quite so scary this time round, having some idea of what to expect after the first cycle.)

Today is Day 1 of Steve’s second treatment cycle: the big chemo day, with doses of both Cisplatin and Velcade interspersed by several litres of saline, a diuretic, an hour’s worth of glucose solution and anti-nausea tablets. And lunch.

Steve has gained a kilo during his week off (reflecting the return of his appetite); all his blood tests came back normal, and no problems with BP, pulse, temperature, blood gasses etc, so cleared for treatment.

Unlike Day 1 of Cycle 1, everything went smoothly this time. However, news of the wasted first dose of Velcade appears to have filtered back to the drug company. As a result, in future, the trial drug will not delivered to the hospital until after the blood tests results are confirmed as clear. We can therefore expect slightly extended hospital visits from now on.

Steve’s CT scan review has been set up for 13 August, so that the results will be available in time to start Cycle 3 of the treatment the following week, assuming it has been effective so far. Please, please, please, PLEASE let that be so!

Our Yorkshire mini-break went so well last weekend, we hope to arrange other visits to see friends during the chemo rest periods, towards the end of each 21-day cycle. However, we also know that Steve tends to feel tired the day after treatment, so my birthday tomorrow will be a low key affair in terms of activity. That said, I’m sure he’ll have enough energy to pop the champagne cork and help me eat my birthday cake!

Whilst on the subject of birthdays, belated greetings to Mary, Stella and Jon who all had birthdays on 24 July, and a big kiss for Martin, Steve’s brother, who shares a birthday (and date) with me. Enjoy yourself!

What is Mesothelioma (Asbestos Cancer)?

Mesothelioma is a rare type of cancer that is believed to affect around 2000 people in the UK each year. It develops when the cells of the mesothelium (a thin membrane that covers the chest and abdomen) start to multiply in a rapid and uncontrollable way and can take up to 60 years to fully develop. In this article I will be discussing this type of cancer in greater detail.

As I already said mesothelioma develops in the mesothelium. The mesothelium is actually divided into two parts. The first is the pleura which lines the lungs. The pleura is comprised of an inner layer and an outer layer which slide over each other as you breath. If mesothelioma develops in this area it is known as pleural mesothelioma and it causes the two layers to become thicker. The second is the peritoneum which lines the abdomen and it also has an inner layer and an outer layer. If the mesothelioma affects this area it is known as peritoneal mesothelioma and it also causes these layers to become thicker.

Both types of mesothelioma can be very painful and lead to a number of undesirable symptoms. Pleural mesothelioma can cause breathlessness, coughing and chest pain. It can also lead to pleural effusion where lubricating fluid in the lungs becomes trapped between the inner and outer layers of the pleura. Peritoneal mesothelioma can lead to abdominal pain, bowel problems and it swelling in the abdomen.

Almost every case of mesothelioma is caused by exposure to asbestos. In the past asbestos was a very popular construction material in the UK. However, as people became more knowledgeable they learnt about the dangers associated with this material. In particular they discovered that the very fine fibres that make up asbestos are easily released when the material is handled. This led to a complete ban on the importing and use of asbestos being imposed in the UK in 1999.

Mesothelioma is a very rare type of cancer and is believed to affect one person in every million. However, it can be deadly. If you have previously been exposed to asbestos you should go see your doctor right away and explain your concerns. Even if it turns out that you do not have this type of cancer it is better to be safe than sorry.

Whilst every intention has been made to make this article accurate and informative, it is intended for general information only. Mesothelioma is a very serious, life threatening condition and you should discuss any concerns, treatments or lifestyle changes fully with your doctor.

Reference: mesothelioma, improving your fitness can help you prevent cancer

End of cycle celebration

We enjoyed an end of cycle celebration this weekend - nothing to do with the Tour de France, but a trip to Huddersfield to see Katie and her partner George, to mark the end of Steve’s first cycle of chemotherapy and enjoy an early birthday celebration.

We had a fantastic Italian meal out on Saturday night and visited Katie and George’s new home for the next academic year, a house in town, rather than a flat in the student halls of residence, at Storthes - a long way from anywhere.

The loft “apartment” at Wellington Mill was huge, double height spaces with a mezzanine level - big enough to sleep six - so plenty of room for Katie and George to stay over with us, and more time to talk and catch up on news.

Lunch on the way out and way back care of the National Trust tea rooms at Calke Abbey and Hardwick Hall extended the night away. It felt like a proper mini-break by the time we arrived back in Oxford…just what we needed to set us up for the second cycle of treatment which starts tomorrow.

3 Potential Peritoneal Mesothelioma Symptoms

Mesothelioma is one of the less common types of cancer affecting around 2000 people in the UK each year. It develops when the linings of the lungs or the abdomen start to grow in a rapid and uncontrollable way. This condition is almost always caused by exposure to asbestos and because of this it is often nicknamed asbestos cancer. If it affects the lining of the abdomen (the peritoneum) it is referred to as peritoneal mesothelioma. In this article I will be outlining three potential symptoms for this type of cancer and discussing the steps you should take if you notice any of these.

The peritoneum (lining of the abdomen) actually has two layers; the inner (visceral) layer which is beside the abdominal organs and the outer (parietal) layer which is next to the abdominal wall. One of the functions of the peritoneum is to secrete a lubricating fluid to allow the abdominal organs to move against one another. When peritoneal mesothelioma occurs it leads to both of these layers becoming thicker. This can then lead to a number of undesirable symptoms that are discussed below:

1) ASCITES:- As the inner and outer layers of the peritoneum become thicker, lubricating fluid can become trapped in this area. This can then lead to a build up of fluid which is referred to as ascites. Ascites can lead to swelling in the abdomen and also cause abdominal pain as the build up of fluid causes the peritoneum to press against the abdominal organs.

2) ABDOMINAL PAIN:- As peritoneal mesothelioma develops and the tumour increases in size it can start to press against the abdominal organs. This often causes abdominal pain and discomfort. As discussed above ascites (another peritoneal mesothelioma symptom) can also lead to abdominal pain.

3) POOR BOWEL FUNCTIONING:- As the tumour increases in size or the ascites cause further swelling the intestines can become blocked. This can make it difficult to excrete waste from the body and also lead to further bowel problems.

If you notice any symptoms similar to those discussed above you should consult your doctor immediately. Upon seeing your doctor you should inform them of the symptoms you have experienced and also tell them if you have previously been in contact with asbestos. Once your doctor has this information they will be able to perform the required tests and determine whether you have peritoneal mesothelioma. Following this they can then discuss the relevant treatment options with you if necessary.

Mesothelioma is one of the rarest types of cancer. In most cases these symptoms will turn out to be something much less serious. However, by seeing your doctor you can get a professional opinion on whether you have mesothelioma or not. If you have had persistent abdominal pains, your abdomen has become swollen or you have had regular bowel problems go see your doctor straight away.

Whilst every intention has been made to make this article accurate and informative, it is intended for general information only. Mesothelioma is a very serious, life threatening condition and you should discuss any concerns, treatments or lifestyle changes fully with your doctor.

Reference: mesothelioma, improving your fitness can help you prevent cancer

Mesothelioma Cancer: Diagnosis Of Mesothelioma Cancer-

Beginning with diagnosis mesothelioma with a review of the patient’s medical history, including any history of asbestos exposure. A complete physical examination including x-rays of the chest or abdomen and lung function tests is performed. A CT (or CAT) scan or an MRI may also be useful. A CT scan is a series of detailed pictures of areas inside the body created by a computer linked to an x-ray machine. In an MRI, a powerful magnet linked to a computer is used to make detailed pictures of areas inside the body. These pictures are viewed on a monitor and can also be printed.

Such sophisticated imaging procedures as MRIs and CT scans usually offer a fairly clear diagnosis, but doctors almost always recommend one more test before coming to a definitive conclusion about any type of cancer. That test is known as a biopsy.

A biopsy, derived from the Greek word meaning “view of the living”, involves removing a sample of fluid or tissue from the affected area and sending it to a pathologist for examination. The biopsy is done by inserting a thin needle into the area in question.

In a biopsy, a surgeon or a medical oncologist (a doctor who specializes in diagnosing and treating cancer) removes a sample of tissue for examination under a microscope by a pathologist. A biopsy may be done in different ways, depending on where the abnormal area is located. If the cancer is in the chest, the doctor may perform a thoracoscopy. In this procedure, the doctor makes a small cut through the chest wall and puts a thin, lighted tube called a thoracoscope into the chest between two ribs. Thoracoscopy allows the doctor to look inside the chest and obtain tissue samples. If the cancer is in the abdomen, the doctor may perform a peritoneoscopy. To obtain tissue for examination, the doctor makes a small opening in the abdomen and inserts a special instrument called a peritoneoscope into the abdominal cavity. If these procedures do not yield enough tissue, more extensive diagnostic surgery may be necessary.

If the diagnosis is mesothelioma cancer, the doctor will want to learn the stage (or extent) of the disease. Staging involves more tests in a careful attempt to find out whether the cancer has spread and, if so, to which parts of the body. Knowing the stage of the disease helps the doctor plan treatment.

If the cancer is found only on the membrane surface where it originated the mesothelioma symptom is described as localized. It is classified as advanced if it has spread beyond the original membrane surface to other parts of the body, such as the lymph nodes, lungs, chest wall, or abdominal organs.

Reference: pleural mesothelioma, peritoneal mesothelioma, mesothelioma causes.

Malignant Mesothelioma Information

Malignant mesothelioma is a type of cancer that is quite rare; it affects only the thin wall of cells that line the internal organs and structures. This lining is called the mesothelium and malignant mesothelioma can manifest itself in three main ways. It can be pleural which affects the lungs, peritoneal which affects the abdominal cavity wall and pericardial which affects the lining in the heart. Experts believe that there is only one way to contract malignant mesothelioma and that is through exposure to asbestos. Asbestos is a naturally occurring mineral that is highly toxic to humans yet was once used in abundance in the building and construction trades.

It was used as it has a very high tolerance of heat and it is remarkably strong, it was also very cheap. It is made of fibres which are microscopic and can be airborne when ceilings covered with asbestos crack or when it is otherwise exposed to the air. When fibres of asbestos get inside the body they cannot be broken down or expelled and this will result in serious scarring of the mesothelioma and inflammation. Once this scarring occurs it is only a matter of time before malignant mesothelioma takes hold in one of its various forms. Symptoms of malignant mesothelioma can initially be quite hard to spot as they can be quite unnoticeable.

As a result they can be passed off as being day to day illnesses and this can cause even more problems as this delay gives malignant mesothelioma even more time to take hold of a person. It has been known for people with malignant mesothelioma to live with their symptoms for up to six months before they seek medical help with them. Symptoms of the various forms of malignant mesothelioma can include - shortness of breath, weight loss, nausea, vomiting, persistent coughing with or without blood in it, abdominal pains, stomach pains, chest pains, pain in the lower back and in some cases swelling of the face and arms and a loss of sensory capabilities.

As these symptoms are so wide ranging and often seemingly unconnected it is no wonder that it can be difficult to obtain a correct diagnosis. Experts now recommend that anyone who has had prior exposure to asbestos at some point in their lives gets checked out for malignant mesothelioma even if they feel fit and well. Doing this could vastly extend a person’s life who could go on to be diagnosed with malignant mesothelioma. Treatment for malignant mesothelioma can vary and surgery should only be an option if the disease is diagnosed in the very early stages. Otherwise it is more common for a person to undergo chemotherapy or radiotherapy to attempt to control the malignant mesothelioma.

Although there is no known cure for malignant mesothelioma it can be controlled for some time if it is caught in time. Otherwise the outlook is not particularly positive and the best that many people with malignant mesothelioma can hope for is to be able to manage their symptoms and pain with painkillers and other medication.

Reference: Mesothelioma?

Remember, remember .......Cycle 1, Day 17

Hindsight is a wonderful thing.

If Steve had known back in the 1960s and 70s that he would be diagnosed with mesothelioma in 2009, he would have made a record of any job he had done where he might have been exposed to excessive amounts of asbestos, a note of his employer at the time, and taken photographs of dust particles in the air, on his clothes or settling on surfaces.

30-40 years after the event, it’s very difficult to remember exactly what happened when, and say with absolute confidence that he was exposed to, or came into contact with, asbestos whilst visiting sites, surveying buildings, working in old MOD huts on airfields, or doing odd jobs in factories in the vacations. Plus, we’ve lost contact with most of the people he worked with during that time, and many of the firms who employed him are no longer trading.

As a result of our failing memories, we came out of the meeting with the solicitor’s rep earlier today with a strong feeling that a successful private claim for compensation for negligence against a former employer would be very unlikely. Still, we’ll see what happens when the solicitor pulls together all the information from various sources to get the bigger picture.

In the meantime, if you have known Steve for a long time, perhaps you can help? Think back - did you help pull down the partitions in the School of Architecture to create the big open plan studio in the early 1970s? Were any of those panels you smashed up made of asbestos? Did you help clear out the building that is now Modern Art Oxford? Did that involve removing or disturbing asbestos? If anyone out there worked with Steve in any other environment where you might have been exposed to asbestos, or know of anyone else who might be able to shed any helpful light on such past events, then please do get in touch.

Enough of the memory games.

There was good news today. Katie’s new laptop arrived safely very early this morning, so we can take it with us when we go to visit her this weekend. The post brought a letter confirming that Steve has been awarded Disabled Living Allowance. It’s no substitute for good health, but it’s some compensation for all the time spent in hospital and the dreams and plans put on hold since diagnosis.

The other news today was not so good. A close friend has swine flu, so any plans for a joint birthday celebration next will be postponed until the infection has cleared up. Get well soon, Sally and please take good care of yourself!

Asbestos and the risk of Peritoneal Mesothelioma

Asbestos is a natural mineral that was once used in the construction and home improvement industries. It was put on ceilings when it was mixed with aertex, it was used to make surfaces semi flame resistant and it was also mixed with cement as it is very strong. At one point asbestos was seen as a revolution for these industries as it was just so versatile - it was also deadly. No one realised at the time that every time they were exposed to asbestos that they were taking their life in their hands and putting themselves in grave danger. Asbestos is now banned but its legacy lives on in the thousands of people who are feeling the after effects of being exposed to it over the years. Exposure to asbestos is directly related to certain types of cancer, including peritoneal mesothelioma which is cancer of the membranes in the abdominal cavity. Peritoneal mesothelioma is the second rarest form of mesothelioma and each year it is responsible for around 20% of the cases of diagnosed mesothelioma. As exposure to asbestos is the only known cause of peritoneal mesothelioma there are two main ways that doctors believe that it can actually reach the abdominal wall. One way is through the digestion of asbestos fibres which is actually easy than most might think. Once in the digestive system the asbestos fibres get stuck in the peritoneum and over time this can result in peritoneal mesothelioma. The second way that asbestos gets to the abdomen is through the lymph nodes and lungs when asbestos is inhaled. In some cases pleural mesothelioma will result in peritoneal mesothelioma ad the asbestos moves through the lungs and into the abdominal cavity if left untreated and undiagnosed for some months. Suspicion of peritoneal mesothelioma is usually made when a patient exhibits signs such as pain in the abdomen, chest or stomach and many suspect hernias are actually created by a tumour caused by peritoneal mesothelioma. Often a misdiagnosis that does not include peritoneal mesothelioma can be made and this can have severe repercussions on the life expectancy of a patient. It is usual for someone who is thought to have peritoneal mesothelioma to have to undergo many tests to get a correct diagnosis and these tests are imaging scans and tissue biopsies. Patients who are found to have peritoneal mesothelioma do not have a good prognosis. However if a diagnosis of peritoneal mesothelioma is made early enough they could have surgery to remove the disease and some cases it can extend a patient’s life span for a few more years. If surgery is not an option then chemotherapy or radiotherapy can help although there is no guarantee that this will make much of a difference. It is essential that a person with peritoneal mesothelioma gets the right kind of treatment for any pain that they experience so that they are as comfortable as they can be. Peritoneal mesothelioma, like the other forms of mesothelioma is highly unpleasant and hard to live with.

Reference: Mesothelioma?

Mesothelioma Stages and Mesothelioma Staging Systems

Mesothelioma stages are categorized in the medical community for evaluative benefit for the physician, the medical institution, participation in clinical trials, and advancements in mesothelioma treatment options. Staging systems are used to define mesothelioma stages; however, mesothelioma stages are far more descriptive for pleural mesothelioma than for peritoneal mesothelioma or pericardial mesothelioma. Mesothelioma staging systems have changed over time. As medical knowledge increases, mesothelioma staging systems advance.

By sectioning a progressive disease into stages, doctors can evaluate mesothelioma treatment options that have been proven successful. By defining mesothelioma stages in a universal staging system, international mesothelioma life expectancy statistics can be gathered. When a staging system gains international acceptance, it contributes greatly to the advancement of mesothelioma treatment options. Grouping similar variables for evaluation is beneficial to developing mesothelioma treatment options for different mesothelioma stages.

In 1976 the Butchart staging system identified four mesothelioma stages for diffuse pleural malignant mesothelioma by location. At stage one, the tumor is in one side of the pleural lining. At stage two, the tumor is malignant and has entered both lungs, and has the potential to spread. In stage three of Butchart’s mesothelioma stages, the tumor has entered the peritoneum (abdomen region), and at stage four, the cancer has spread through the blood stream.

It was simple, thus gained acceptance. However, it fails to address crucial issues. Medical experts suggest it fails to make survival correlations with mesothelioma stages. The Butchart mesothelioma staging system in its originality is obsolete for mesothelioma life expectancy statistics, however other mesothelioma stages have been developed from it, and many cancer institutions modify it for their evaluative purposes.

In the 1980s Chahinian added detailed tumor stages, lymph node stages and metastases stages to the pleural mesothelioma staging system. This staging system is referred to as TNM and is used within elaborative staging systems. In 1990 the UICC (Union Internationale Contre le Cancer) expounded on Chahinian’s mesothelioma stages. The Butchart, Chahinian and UICC mesothelioma staging systems were based on specific institution experience.

In 1999 the Bingham Hospital introduced a pleural mesothelioma surgical staging system in the Journal of Thoracic and Cardiovascular Surgery. The IMIG (International Mesothelioma Interest Group) in a 1995 Journal of Chest from the American College of Chest Physicians proposed international acceptance for a detailed universal staging system. This staging system demands precise tumor location, and is based on TNM and the International Lung Cancer Staging System.

Medical institutions will use the mesothelioma stages and staging system practical for their internal evaluative purposes. But the mesothelioma patient should be aware when discussing mesothelioma life expectancy and prognosis that mesothelioma staging systems differ, and staging systems still undergo scrutiny. No staging system includes all variables for treatment and prognosis. Factors such as tumor subtypes can make a significant difference in prognosis.

In its basic form, mesothelioma has two stages - localized and advanced. In most staging systems, localized mesothelioma is considered stage one. Stages two through four are advanced mesothelioma stages. Mesothelioma stages are generally defined by location, the severity of the tumor, or surgical needs. The stages of mesothelioma are dependent on the staging system used.

Mesothelioma stages are important considerations in treatment and prognosis. An accepted universal mesothelioma staging system can expedite medical research to find effective mesothelioma treatment options. Advances in clinical research will continue to contribute to the development of defining mesothelioma stages until precise correlations can be made. Until then, staging systems are a universal answer to evaluating mesothelioma treatment.

Reference:

avisolutionz

All about Mesothelioma

Mesothelioma is a form of cancer that is normally caused by asbestos exposure. Mesothelioma is cancer that occurs in the mesothelium.

Mesothelioma: Mesothelioma is a type of cancer affecting the cells of mesothelial lining in the chest and abdomen. Mesothelioma cancer can develop in the tissues covering the lungs or the abdomen. Mesothelioma has also been found in the stomach and other abdominal organs but it is much rarer in those areas than are both pleural mesothelioma and peritoneal mesothelioma. Mesothelioma can also occur in the ovaries and scrotum. Mesothelioma invades the chest wall or the esophagus during the second stage.Mesothelioma also takes a long time to develop (typically 15-40 years), so patients today could have been exposed prior to the 1980s when asbestos was not highly regulated. Mesothelioma is not caused by smoking, as lung cancer so often is.

Symptoms: Symptoms One of the most common symptoms of mesothelioma is an accumulation of fluid between the lining of the lung and the chest cavity. Symptoms include: abdominal painascites, or an abnormal buildup of fluid in the abdomen a mass in the abdomen problems with bowel function weight loss. Symptoms such as trouble swallowing, pain, or swelling of the neck and face can be indications that the cancer has spread beyond the mesotheliom to other parts of the body. Symptoms of pleural mesothelioma include persistent pain in the chest and severe difficulty breathing caused by pleural effusion, or an accumulation of fluid in the pleural lining Cough, weight loss, and fever are also common symptoms. Symptoms of peritoneal mesothelioma include weight loss and abdominal pain and swelling due to a buildup of fluid in the abdomen. Symptoms of mesothelioma may not appear until 20 to 50 years after exposure to asbestos. Diagnosis: The key to long-term survival from treatment of mesothelioma is early diagnosis, which enables the greatest potential for success from standard therapies. Diagnosis begins with a review of the patient’s medical history, including any history of asbestos exposure. Diagnosis of Mesothelioma is based on a pathological exam, more commonly referred to as a biopsy.Since this disease can be hard to diagnosis and costly to treat, it may require the consultation of an experienced attorney. When conclusive diagnosis cannot be made from fluid samples, diagnosis is often made through a surgical procedure called a throrascopy.The average age at diagnosis of mesothelioma is between 50 and 70 years old, with men being affected three to five times more often than women. The diagnosis may be suspected with chest X-ray and CT scan, and is confirmed with a biopsy (tissue sample) and microscopic examination. The median survival time is 17 months, with ten percent of patients living for three years after diagnosis.

Conclusion: Mesothelioma is a deadly cancer which is fairly rare although in the last few decades the number of people who have died from it have dramatically increased. Mesothelioma is a rare form of cancer, but the deadliest one of all. Mesothelioma is a rare form of cancer and only affects between 2,000 and 3,000 people in the United States per year. Mesothelioma is less common in African Americans than in white Americans. Mesothelioma is rare in people under age 55. National Cancer Institute stats show that 3000 new diagnosis of malignant mesothelioma is reported each year. Mesothelioma is not always fatal and that is the hope to hold on to.

Reference: http://www.mesothelioma.greatreview.info

Those words you like to hear (or read)

It’s funny how just a few words can lift the spirits.

Here’s just a small selection of words and phrases that have had that effect on me/us recently:

“I’m still hungry” Steve, this evening

“I feel remarkably like I’m getting back to normal” Steve, earlier today

“I think I’ve got my appetite back” Steve, yesterday

“My temperature has gone down” Steve, on and off over the last few days

“Your booking is confirmed” LateRooms.com earlier this afternoon (somewhere nice to stay in Huddersfield when we visit Katie this coming weekend)

“We have double booked the studio (our mistake) but can offer you an upgrade to a two bed apartment at no extra charge” Heritage Lofts, a few minutes later (somewhere even nicer to stay!)

“You bid has been successful” E-bay, earlier today (a computer for Katie, to replace the one that’s just died…)

“Next year I should have some really good project work to be proud of, along with enough spare time for a part time job and any time off, if I need it”, Katie’s plans for the next academic year

“I’ve brought you something from the allotment” a bag of freshly picked lettuces, courgettes, fennel, and raspberries from Jean, this weekend

“It’s good to see you both looking so well!” Rebecca, who dropped by last Friday

“Come here and let me give you both a big hug” Athena, when we bumped into her walking into town last week

“You would be welcome here any time, as you know…” e-mail from Andy and Dave, Peak District

“We’re back. Come round for a meal tomorrow?” Ian and Ruth, back from Vietnam for a short visit (the answer was yes, thank you, and jolly good it was too!)

“Keep blogging…I appreciate being in touch with you, without having to bother you”, Maralyn in Bognor

“You sound amazingly determined and as positive as possible in the circumstances - well done!” Angela in Brussels

…not to mention all the other e-mails, cards, messages and uplifting conversations which have helped keep us feeling positive over this last month or so….

Mesothelioma Support Systems

Mesothelioma is a rare cancer that affects the mesothelium, a thin layer of tissue that surrounds almost all of the internal organs. • Pleural mesothelioma affects the tissue surrounding the lungs • Peritoneal mesothelioma affects tissue in the abdomen • Pericardial mesothelioma affects tissue surrounding the heart Pleural mesothelioma is the most common form of this disease. Two to three thousand people are diagnosed each year with mesothelioma. Most new cases affect white men in the fifty to seventy year old age group. Since this disease is insidious and difficult to detect, mesothelioma is usually in an advanced stage when first diagnosed. The average survival rate is one year. However, if found early and treated aggressively, chances of survival improve. One out of five diagnosed with mesothelioma is able to survive for five years after diagnosis and treatment. With new advances in research and treatment continuing to be discovered, survival rates are destined to improve. Significant breakthroughs have been produced by research for mesothelioma patients and more options are becoming available to manage life with this disease and improve the quality of life. Support is Imperative Still, a diagnosis of mesothelioma is devastating to the patient, family and friends. They must take the time to absorb the news of the diagnosis and to grieve and feel the emotions of hearing this diagnosis. Then it is important that the patient, family and friends regain a sense of control of the situation instead of the situation controlling them. They must learn everything they can about mesothelioma. They should turn to their healthcare provider for information to better understand this disease. They can consult the National Cancer Institute (NCI) and the American Cancer Society (ACS). Both these organizations have very informative websites. Family and friends can help with everyday tasks such as getting to appointment, scheduled treatments and grocery shopping and household chores. The patient must learn to ask for and accept help if they have not done so in the past. Find out about support groups in your community. Sometimes only someone with the same problems can offer just the right answer to a question or concern. Online support message boards, such as the American Cancer Society’s Cancer Survivor Network can offer solutions, while allowing the questioner to remain anonymous.

Reference: mesothelioma attorneys, Parker, Dumler & Kiely, LLP

Understanding a Mesothelioma Diagnosis

After receiving a mesothelioma cancer diagnosis it’s important to take necessary steps in order to ensure that you and your family will be protected and cared for during this time.

In order to do so, physicians suggest that you create a list of questions for both your family and doctor before finding out your diagnosis.

Researchers found that if patients make an initial list of questions and receive answers before they know the diagnosis then they are better able to cope with the results.

Types of Mesothelioma Cancer

There are three types of mesothelioma cancer, all of which need proper treatment and can be life altering upon diagnosis.

These three forms of mesothelioma are:

• Peritoneal Mesothelioma - This type affects the lining in the abdominal cavity
• Pericardial Mesothelioma - Affects the area surrounding the heart
• Pleural Mesothelioma -Affects the lining of the lung

It is important to understand what type of mesothelioma you have once a diagnosis is given.

How the Diagnosis is Determined

After receiving your diagnosis, it is essential that you find out how your doctor determined whether or not you have the illness.

Reports claim that the only reliable way to know whether an individual has mesothelioma cancer is through a tissue biopsy.

Fluid biopsy’s are often given but have shown a high percentage of negative results when mesothelioma cancer is present.

Have you or someone you know recently been diagnosed with mesothelioma cancer? If so, please contact mesothelioma treatment centers to become better informed on the illness and the treatments that are available.

Reference: Joe Silver

and now for something completely different...Cycle 1, Day 11

That’s it - the last dose of Velcade in Cycle 1 of the chemotherapy has been given. We can now look forward to something completely different: ten whole days without a planned hospital visit. The last time that happened was prior to Steve’s diagnosis, between the first CT scan in late May which showed up fluid on the lung and going into hospital in early June for the chest drain, thoracoscopy and pleurodesis.

Fortunately, the hiccup with Steve’s temperature on Wednesday has not affected his red cell or blood platelet count, so he was cleared for treatment at this morning’s visit. Before leaving for the “week off”, we talked some more about the chemo’s side effects, to get a better idea of what to expect in the coming months, especially as we’re hoping to spend a little bit of time visiting away from Oxford at the end of some of the three week cycles.

Nausea/sickness is caused mainly by Cisplatin, so should not be a problem for more than a few days after the start of each cycle. However, tingling and numbness in hands and feet and ringing in the ears are particular side effects of Velcade which (if they occur) have a cumulative impact. Something to watch out for….

The most common side effect of all chemo is tiredness/fatigue - but people react differently. In some, fatigue peaks and troughs follow the pattern of treatment, fading away in “rest” weeks. In others, tiredness can build up over time, increasing towards the end of the six cycle course of treatment. Sometimes, it can be a combination of the two - peaks and troughs in weeks 1 and 2 and respite in week 3, gradually ratcheting up over time. Other people recognize the onset of fatigue, modify their behaviour accordingly, and don’t notice much change as the months pass. We’ll just have to wait and see what happens to Steve.

The most significant side effect of chemo is the way it suppresses the immune system. The importance of minimizing the risk of infection was impressed upon us yet again, and acting swiftly if his temperature reaches 37.5C, even if it means phoning the hospital at 2 am. Otherwise, being careful about hand and food hygiene, using a hankie and avoiding those with coughs and sneezes wherever possible is the order of the day. Common sense really.

The jury is still out on how the hospital will deal with swine flu, should it affect staff, patients or contacts of either. However, there are facilities to isolate patients with infections and those undergoing chemotherapy are recognized as a vulnerable group and will be treated accordingly.

We also learned that Velcade costs over £3000 per cycle rather than per dose, as we thought originally. However, at £400 or so per mil, it’s still hugely expensive. It had better be worth it!

Although no hospital appointments for 10 days, the meso stuff doesn’t go away completely in the meantime:

The trial nurse will be in touch next week to sort out the arrangements for a CT and X-ray as part of the review of Steve’s treatment at the end of Cycle 2.

We will also be visited by solicitors experienced in dealing with mesothelioma claims, contacted through Prospect (my union). We’re not confident that Steve’s exposure to asbestos can tracked back to a particular time and/or place. However, bearing in mind that no compensation was available when Steve’s dad died as a result of mesothelioma, it’s something we ought at least to explore now the family has been struck by it again.

That’s enough meso-mania - time to think about nice things to do in the next ten days!

One last thing: Debbie Brewer (http://www.mesothelioma-and-me.com) was diagnosed with mesothelioma in November 2006. Following a procedure called chemoembolization, she is now in remission. Debbie is having a party today to celebrate being 50. Happy birthday Debbie and many, many happy returns :)!

Smoking and Mesothelioma

Mesothelioma is a rare form of cancer that occurs in the mesothelium, a thin layer of tissue that covers almost all of the internal organs. Pleural mesothelioma affects the pleural lining of the lungs. Pleural mesothelioma accounts for over 70% of all mesothelioma cases. Peritoneal mesothelioma affects the tissues of the abdomen and pericardial mesothelioma affects the pericardium, or lining of the heart. Many factors contribute to the increased risk of mesothelioma such as inherited traits, environment, general health status and lifestyle choices. Exposure to asbestos is the primary risk factor for contracting mesothelioma. Asbestos fibers are found in insulation, cement, brakes, shingles, flooring and many other products. Smoking increases the risk of developing mesothelioma in workers exposed to asbestos. Symptoms and Signs The symptoms and warning signs differ depending on the organs involved. Pleural mesothelioma symptoms may include:
• Shortness of breath
• Pleurisy (painful breathing)
• Painful cough
• Chest pain under ribcage
• Lumps under skin of chest
• Unexplained weight loss
• Dry cough
The symptoms of peritoneal mesothelioma may include:
• Abdominal pain
• Abdominal swelling
• Constipation and/or diarrhea
• Lump in abdomen
• Unexplained weight loss
Pericardial mesothelioma symptoms may present with difficulty breathing and/or chest pains, while mesothelioma of the tunica vaginalis may reveal a mass on the testicle. Various diagnostic tests are required to confirm the diagnosis of mesothelioma. Treatment depends on the extent of the disease. Mesothelioma may lead to death. People afflicted with mesothelioma die from related complications such as lung failure, heart problems, stroke and other causes.

Reference: mesothelioma attorneys, Parker, Dumler & Kiely, LLP

One month later....Cycle 1, Day 10

It’s one calendar month to the day since Steve was diagnosed with mesothelioma and our lives took a different and unexpected direction. In some ways, it feels like a lot longer, in other ways, time seems to have flown by - we are amazed at all the things that have happened since 16 June:

• holiday cancelled and insurance claim submitted
• family and friends told of diagnosis and blog started
• desk cleared at work and arrangements put in place for the rest of the summer
• 14 hospital appointments, including visits to the chest clinic, oncology clinic, screening for the drug trial, CT scan, X-Ray, one radiotherapy planning session, three radiotherapy treatment sessions and three chemo sessions to date…plus a trip to the doctor for the pneumococcal jab
• Industrial Injuries Disablement Benefit and Compensation applied for and awarded; Disabled Living Allowance application in the pipeline…
• taken part in medical research: TIME Trial (chest drain size and pain relief); Cancer Research UK Study of Occupation and Cancer; Velcade Phase II Drug Trial and the related genetics sub-study
• enjoyed a retirement tea party, a 60th birthday party, two garden lunches and an indoor lunch with various groups of friends; entertained visitors at home and visited family in Bristol
• survived a heat wave, enjoyed Wimbledon, rugby, cricket and the Tour de France, and finally planted the lettuce seeds to provide fresh salad and the window boxes for a fresh outlook!
• been overwhelmed and greatly touched by the all good wishes, and messages of love and support from family, friends, neighbours and colleagues

It’s also been a time of contrasts and contradictions:

Waiting to hear whether Steve was on the Velcade trial seemed to take forever, as did setting up the radiotherapy and chemotherapy sessions, then suddenly it was almost non-stop action, with hardly a day to catch breath between hospital visits.

Feeling almost normal, whilst being assessed as 100% disabled seemed unreal, as did the fact that everyday life carried on, regardless of the life shattering news that Steve has an incurable cancer.

Wanting to start treatment as soon as possible but fearing the side effects pulled us in different directions.

On the one hand, our lives for the next five months are planned almost exclusively around a 21 day chemo cycle. On the other hand, we take each day at a time, depending on what needs to be done and how Steve is feeling.

We think about the future but concentrate on making the most of the here and now. Our perspective on life as changed and priorities reassessed. The emotions are still raw, but we have tried really hard to be positive in our outlook…and most of the time we succeed.

By the time I write the monthly review on 16 August, it will almost be the end of Steve’s second cycle of chemo - a good time to stand back and reassess how things are going two months after diagnosis.

In the meantime, although a few of our friends hate any sort of communication via computers, many others have found it helpful to read this blog to keep up-to-date with news and progress. Apologies if it sounds like stream of consciousness stuff at times (it is - that’s my therapy!) and for any typos and bad grammar. I’ll try to post some more photos from time to time to improve the presentation.

Please continue to keep in touch with us - knowing that you are all out there sending positive thoughts really does help!

Thank you, everyone.

A bit under the weather, but otherwise on form.........Cycle 1, Day 9

One of the downsides of chemotherapy is that it compromises the body’s immune system, making infections more risky than would otherwise be the case.

Although I felt better when I woke up this morning, it wasn’t long before we realized that I had given my sore throat to Steve. His temperature started rising from 36C this morning and crept up during the day to peak at 37.3C this afternoon. That may not seem like a high fever, but it was too close for comfort to the threshold of 37.5C which triggers a trip to hospital for intravenous antibiotics and a dose of antiviral medicine.

Because Steve was feeling under the weather, I abandoned plans to attend a meeting in London and stayed home to play the role of temperature monitor. The good news is that his temperature had gone down to below 37C this evening, so no crisis. However, he feels very washed out and has gone to bed early.

The morning post brought what I hope will be the last piece of paper in the jigsaw of our travel insurance claim for the cancelled holiday to Turkey - a letter from the airline confirming that we had not taken the flights and that no refund had been given. Staying at home this afternoon meant I had the opportunity to finish the claim. Let’s hope Europe Assist sort it out promptly….

The other document to arrive this morning was the Report of Diagnosis on official form DS 1500. This is a key document to claiming other allowances which the MacMillan Cancer Benefit Advisors say Steve is entitled to as a mesothelioma sufferer. Filling in the form for Disabled Living Allowance kept me occupied for the rest of the afternoon. It wasn’t something that loomed large when we first looked through the benefits guidance, but today’s brush with infection brought home to me just how vulnerable Steve is as a result of the chemo - let alone the cancer - so it was worth spending the time filling in the form (anything to avoid the pile of ironing……)

Tomorrow it will be a calender month since Steve was diagnosed. Time for a review, perhaps?

Mesothelioma Misconceptions and Myths

Asbestos exposure is the primary risk factor for contracting mesothelioma, and workers handling asbestos fibers are at the greatest risk for mesothelioma.

There are many misconceptions and myths surrounding the diagnosis of mesothelioma. One of the misconceptions is that mesothelioma is lung cancer. Mesothelioma that originates in the pleural lining of the lung has similar symptoms but is not true lung cancer. Treatments can vary greatly between lung cancer and mesothelioma of the pleural lining of the lung.

Mesothelioma Myths

A mesothelioma myth is that only asbestos workers develop mesothelioma. While the overwhelming majority of mesothelioma cases are attributable to asbestos exposure, other cases of people not exposed to asbestos do exist. Families exposed to the clothing and shoes brought home by workers have contracted mesothelioma.

Another misconception is that a small amount of exposure is not harmful. No amount of exposure to asbestos is safe. The smallest particle of asbestos fiber lodged in the pleural lining can result in mesothelioma. The misconception that there is no hope for mesothelioma victims is perhaps the most troubling. Doctors and researchers are working every day towards finding a cure and eradicating this disease.

Mesothelioma is, in fact, a rare form of cancer that occurs in the mesothelium, a thin layer of tissue that covers almost all of the internal organs of the human body.

• Pleural mesothelioma affects tissue surrounding the lungs
• Peritoneal mesothelioma affects the tissue surrounding the abdomen
• Pericardial mesothelioma affects tissue surrounding the heart
• Mesothelioma of the tunica vaginalis occurs in the lining of the testicles

Two to three thousand people are diagnosed each year with mesothelioma. Pleural mesothelioma is the most common form seen in this disease.

Warning Signs of the Disease

Mesothelioma is difficult to diagnose due to the subtle changes affecting the body in the early stages of the disease. The symptoms of mesothelioma are often ignored and attributed to common everyday ailments. People with pleural mesothelioma experience lower back pain or side chest pain and shortness of breath. They may also have difficulty swallowing, a persistent cough, fever, weight loss and show signs of fatigue. Peritoneal mesothelioma symptoms include abdominal pain, weight loss, nausea and vomiting. Pericardial mesothelioma symptoms include trouble breathing, shortness of breath and chest pain. Mesothelioma of the tunica vaginalis may present as a mass on one or both testicles.

Reference: mesothelioma attorneys, Parker, Dumler & Kiely, LLP

...and then things do not go as smoothly as planned...Cycle 1, Day 8

Today was one of those days where you just know from the outset that things will not go as smoothly as they might.

I woke up with a slight sore throat and a bit of a temperature to news on the radio about the spread of swine flu (although I’m more worried about passing on an infection to Steve now that his immune system is compromised by the chemo, than getting a bug myself).

Drivers on the main road were reluctant to let us into the stream of traffic at the end of our street, even though it had come to a standstill just a little further on…

Car parks near the entrance to the Cancer Centre at the hospital were all full, in spite of the signs saying SPACES, so we had a bit of a trek from one of the more far-flung car parks (but at least it had stopped raining by then).

The receptionist at the Oncology Short Stay Centre had no record of the visit, but the magic words Velcade Trial eventually did the trick. After all the normal observations were completed, we were told the bad news that the computer in the lab which analyses blood samples had broken down, as had the back-up facility on the ward. Steve’s blood samples would have to be couriered to another hospital for analysis before he could be cleared for today’s chemo.

We knew from the experience last Tuesday that once made up, Velcade has a very limited shelf life - and has to be thrown away if not administered quickly. We were acutely aware (as were the staff) that a long delay getting the results back from the other hospital would be bad news, so we just kept our fingers crossed and waited and waited, and read the paper, and had lunch, and waited…..

The “all clear” was eventually given with about 40 minutes to spare; the chemo itself was over in minutes.

We arrived home about four hours after setting out, a rather longer trip than envisaged, having witnessed a distracted cyclist ride into the back of the car in front of us on the journey home. We gave her a very wide berth when we caught up with her a bit further along. As I said at the start, it’s one of those days……

Almost normal .......Cycle 1: Days 5, 6 and 7

Three whole days with no hospital appointments. What to do on this long weekend off?

Boring though it sounds, just being able to walk into town for a dose of browsing and retail therapy on Saturday had its peculiar attraction, being such a routine, everyday activity at a time when hospital visits for chemotherapy have become the norm.

After a showery start, the sun came out at lunchtime on Sunday for Roger and Stella’s lunch in the garden at Cothill. It was good to meet up with friends who go back a long, long way and to catch up on news of allotments, children, grandchildren, work and leisure, and an imminent retirement. The garden looked splendid, the food and wine were excellent, as was the company - thanks Stella and Roger for a very enjoyable afternoon and to everyone for their good wishes and support.

Going to London for a work-related meeting on Monday reinforced the feeling that things were almost normal. Although I was anxious about leaving Steve alone for more than an hour or two, I needn’t have worried unduly - he had a quiet day and managed to stay awake till our usual bed time.

How nice to be almost normal for a change!

Mesothelioma Symptoms and Tests for Mesothelioma

Mesothelioma symptoms are progressively slow and take years to surface. Early medical testing to confirm the etymology of mesothelioma symptoms can add years on to your life, and can even offer you salvation from a normally fatal disease. If you’ve been exposed to asbestos and are experiencing mesothelioma symptoms, notify your doctor of any asbestos exposure and monitor your symptoms from their onset. Even short term asbestos exposure can result in non-fatal pleural diseases. Keeping a journal of your mesothelioma symptoms can assist you and your physician in medical diagnosis, and it may contribute to an asbestos claim.

The symptoms of mesothelioma will differ based on their origin. Pleural mesothelioma starts in the lung area, peritoneal mesothelioma starts in the abdomen area, and pericardial mesothelioma starts dangerously close to the heart. Benign and malignant mesothelioma have similar symptoms, and similar tests. Weight loss is a well-documented symptom in the majority of mesothelioma cases. Abdominal pain is a primary symptom of peritoneal mesothelioma. Both pleural mesothelioma symptoms and peritoneal mesothelioma symptoms include chest pain and shortness of breath.

Pleural mesothelioma medical tests look at the pleural lining, lung fluid, inflammatory conditions, tissue, blood counts and cells to help determine what type of pleural activity is going on inside your lungs. The tests will help diagnose whether your mesothelioma symptoms might be due to pleural effusion, diffuse pleural thickening, asbestosis or other asbestos caused diseases that aren’t necessarily as dangerous as pleural mesothelioma, but can be due to their respiratory nature.

A CT scan will identify pleural thickening better than a chest X-ray. MRI and PET scans can then determine whether the pleural disease is diffuse pleural thickening or if it is malignant pleural mesothelioma. Blood tests can also give an indication of the possibility of cancer. Once cancer is the suspected cause of your mesothelioma symptoms, a biopsy will take place. Thoracentesis removes pleural fluid for diagnosis. Thoracoscopy uses a “camera” (endoscope) inserted into the chest for diagnose and a sample of tissue is taken at that time. Pleural mesothelioma starts in the pleural region, but it will progress to attach other major body organs, such as the heart or abdominal area.

Abdominal pain and bowel restrictions are common peritoneal mesothelioma symptoms. If peritoneal mesothelioma is suspected after the traditional CT, MRI and PET scans, a peritoneoscopy or paracentesis is likely. Peritoneoscopy is done in the hospital with a camera-like instrument called a peritoneoscope. Peritoneal mesothelioma has also been incidentally discovered while performing similar procedures involving infertility examinations on women. A fluid sample is obtained in a process called paracentesis. This involves a needle going into your abdomen to get a sample of the fluid.

Pericardial mesothelioma symptoms always involve severe chest pain. This is a cancer invading the sac over the heart. The pericardial mesothelioma patient may even experience heart failure. Blood tests, CT scans, MRIs and PETs are just the beginning of pericardial mesothelioma medical tests. There will be pulmonary tests and potentially dangerous biopsies. Pericardial mesothelioma symptoms are frequently misdiagnosed. The cancer is very rare, and many well-known diseases display the same symptoms as pericardial mesothelioma. It is often during surgery that pericardial mesothelioma is discovered, and then it is usually too late.

Mesothelioma symptoms can be suggestive of many cancers or diseases. Medical testing for mesothelioma symptoms requires a long battery of tests to discover symptom origins. Medical tests for mesothelioma symptoms can expedite mesothelioma treatment. Symptoms take decades to surface. Start recording your mesothelioma symptoms and start your tests early. It’s better to test for mesothelioma symptoms early, before it’s too late.

Reference:

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